- Stimulate natural collagen and elastin production
- Improve skin hydration at a deep level
- Enhance tissue repair and regeneration
- Reduce inflammation and oxidative stress
- Strengthen the skin’s overall structure and resilience
Skin regeneration, from the inside out
What Are Polynucleotides?
Polynucleotides are one of the most exciting advancements in modern aesthetic medicine. Rather than simply adding volume or temporarily hydrating the skin, they work with your body's own natural healing processes to genuinely repair and renew the skin from within.
Polynucleotides are highly purified DNA molecules derived from natural sources and used in injectable form to stimulate the skin's natural repair and regeneration. When introduced into the skin, they activate fibroblasts (the cells responsible for producing collagen and elastin) and improve overall skin quality at a deep, cellular level
The result is firmer, healthier, more youthful-looking skin without the use of synthetic fillers or volume-adding products. That's what makes them so popular with patients looking for subtle, regenerative rejuvenation rather than dramatic or artificial-looking changes.
How Do Polynucleotides Work?
Polynucleotides work by improving the skin's internal structure rather than just treating the surface. Once injected, they get to work in several powerful ways
Over time, this leads to stronger, healthier, more youthful-looking skin, with results that continue to build naturally as your skin renews itself from within.
- Anti-Inflammatory & Skin-Calming: Helps reduce redness and inflammation, ideal for sensitive, acne-prone or rosacea-prone skin.
- Improves Under-Eye Dark Circles: Strengthens the delicate skin under the eyes, reducing dark circles, crepiness and a tired appearance.
The Benefits of Polynucleotide Treatment
Polynucleotides go beyond traditional skin boosters by working at a cellular level to repair, regenerate and restore your skin naturally.
- Stimulates Collagen & Elastin Production: Encourages your skin to produce its own structural proteins, restoring firmness, elasticity and youthful volume.
- Deep Skin Regeneration & Repair: Works at a cellular level to repair damaged skin and promote long-term skin health rather than temporary results.
- Improves Skin Texture & Tone: Smooths rough skin, refines pores and creates a more even, radiant complexion.
- Softens Fine Lines & Laxity: Gradually softens lines and tightens loose skin for a natural, refreshed appearance.
- Intense Hydration & Plumping: Attracts and retains moisture within the skin for a healthier, dewy look.
- Repairs Sun Damage & Scarring: Supports skin healing and renewal, softening pigmentation, acne scarring and environmental damage.
- Minimal Downtime, Maximum Results: A quick, minimally invasive treatment that slots easily into your routine.
Areas Treated & Who It's Suitable For
Polynucleotides are wonderfully versatile and can be used safely across multiple areas of the face and body, including some of the more delicate areas where traditional fillers aren't always suitable.
- Face: Overall rejuvenation, brightening and improved skin quality.
- Under-Eye Area: Softens dark circles and refreshes a tired, hollow-looking eye area.
- Neck: Improves crepey, lined skin for a smoother, firmer appearance.
- Décolletage: Softens wrinkles and sun damage from years of exposure.
- Hands: Restores plumpness to one of the first areas to show visible ageing.
Polynucleotide treatment is ideal if you:
- Want natural-looking, subtle skin rejuvenation
- Are noticing early signs of ageing such as fine lines or dullness
- Have dehydrated, tired-looking skin in need of a deeper boost
- Are concerned about laxity, sagging or loss of firmness
- Want to improve under-eye dark circles, crepiness or hollowing
- Prefer regenerative treatments over volumising fillers
What to Expect From Your Treatment
Your journey begins with a detailed consultation, where we'll assess your skin, talk through your concerns and create a personalised treatment plan designed around you.
The treatment itself involves a series of small, precise injections into the targeted areas. Most patients experience minimal discomfort, with the whole appointment typically taking around 30 to 45 minutes. You may notice some slight redness, swelling or small bumps at the injection sites afterwards. This is completely normal and usually settles within a few hours to a couple of days.
Polynucleotide results develop gradually as your skin regenerates from within. Unlike treatments that deliver an immediate change, this is a slow-build, long-term investment in genuinely healthier skin.
- Initial improvements visible within a few weeks
- Optimal results after a complete course of treatments
- Initial improvements visible within a few weeks
- Optimal results after a complete course of treatments
Most patients benefit from a starting course of 2 to 3 treatments, spaced around 3 to 4 weeks apart, with maintenance sessions every 6 to 9 months to keep results looking their best.
Why Choose Dermal Designs for Polynucleotides
Polynucleotides are a medical-grade treatment that should only ever be carried out by an experienced, qualified healthcare professional. At Dermal Designs, every treatment is delivered by Joe Church, a registered pharmacist and independent prescriber with over 20 years of healthcare experience and more than a decade in aesthetics.
- Treatments delivered by a registered pharmacist and independent prescriber
- Clinic registered with Healthcare Improvement Scotland
- Healthcare Improvement Scotlandmember
- Premium, clinically proven polynucleotide products
- Personalised treatment plans, never one-size-fits-all
- Honest, no-pressure consultations
- Calm, welcoming clinic in the heart of Perthshire
- Affordable pricing with a friendly, down-to-earth approach
Frequently Asked Questions
Q1: How are polynucleotides different from dermal fillers?
Dermal fillers add volume to specific areas of the face. Polynucleotides don’t add volume — they regenerate and repair the skin itself, improving its underlying quality, hydration and elasticity. They can also be used alongside fillers as part of a wider treatment plan.
Q2: How long do polynucleotides take to work?
When administered by a qualified medical professional using premium, regulated products, dermal fillers are considered a very safe non-surgical treatment. As an experienced pharmacist prescriber and Healthcare Improvement Scotland practitioner, Joe carries out every treatment to the highest medical standards.
Q3: How long do results last?
When administered by a qualified medical professional using premium, regulated products, dermal fillers are considered a very safe non-surgical treatment. As an experienced pharmacist prescriber and Healthcare Improvement Scotland practitioner, Joe carries out every treatment to the highest medical standards.
Q4: Is the treatment painful?
When administered by a qualified medical professional using premium, regulated products, dermal fillers are considered a very safe non-surgical treatment. As an experienced pharmacist prescriber and Healthcare Improvement Scotland practitioner, Joe carries out every treatment to the highest medical standards.
Q5: Is there any downtime?
When administered by a qualified medical professional using premium, regulated products, dermal fillers are considered a very safe non-surgical treatment. As an experienced pharmacist prescriber and Healthcare Improvement Scotland practitioner, Joe carries out every treatment to the highest medical standards.
